Lactic acidosis in diabetic ketoacidosis

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What Induces Diabetic Ketoacidosis or Lactic Acidosis in Diabetic Alcoholic Patients Complicated with Chronic Calcific Pancreatitis?

Diabetic ketoacidosis (DKA) and lactic acidosis (LA) are severe metabolic acidosis which develop in diabetic alcoholic patients. The insulin deficiency and elevation of glucagon leads to increased hepatic glucose output, and induces the release of free fatty acids (FFA) from ad ipose tissue, which are associated with the development of DKA. The insulin deficiency also plays a critical ro le in ...

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Phenformin-induced lactic acidosis in an older diabetic patient: a recurrent drama (phenformin and lactic acidosis).

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Acidosis: The Prime Determinant of Depressed Sensorium in Diabetic Ketoacidosis

OBJECTIVE The etiology of altered sensorium in diabetic ketoacidosis (DKA) remains unclear. Therefore, we sought to determine the origin of depressed consciousness in DKA. RESEARCH DESIGN AND METHODS We analyzed retrospectively clinical and biochemical data of DKA patients admitted in a community teaching hospital. RESULTS We recorded 216 cases, 21% of which occurred in subjects with type 2...

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Lactic Acidosis

Lactic acidosis is a form of metabolic acidosis due to the inadequate clearance of lactic acid from the blood. Lactate is a byproduct of anaerobic respiration and is normally cleared from the blood by the liver, kidney and skeletal muscle. Lactic acidosis occurs when the body's buffering systems are overloaded and tends to cause a pH of ≤7.25 with plasma lactate ≥5 mmol/L. It is usually caused ...

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Lactic acidosis.

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ژورنال

عنوان ژورنال: Case Reports

سال: 2014

ISSN: 1757-790X

DOI: 10.1136/bcr-2014-203594